50-04-4 MSDS - Cortisone acetate
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Cortisone acetate

Identification
Name Cortisone acetate
CAS Registry Number 50-04-4
Synonyms 11,20-trione,17,21-dihydroxy-pregn-4-ene-21-acetate;11-dehydro-17-hydroxycorticosterone-21-acetate;11-dehydro-17-hydroxycorticosteroneacetate;17,21-dihydroxypregn-4-ene-3,11,20-trioneacetate;20-trione,21-(acetyloxy)-17-hydroxy-pregn-4-ene-11;21-(acetyloxy)-17-hydroxypregn-4-ene-3,11,20-trione;21-acetoxy-17,alpha-hydroxy-3,11,20-triketopregnene-4;21-acetoxy-17,alpha-hydroxypregn-4-ene-3,11,20-trione
Molecular Structure Cortisone acetate   50-04-4
Molecular Formula C23H30O6
Molecular Weight 402.48
mp: 237-240 ℃(lit.)
Safety Statements: 22-36/37
Supplier
Lightchem Inc
Supply Precious metal catalyst
OLED Materials etc.
www.lightchem.com
 
Wiki & MSDS
50-04-4.pdf
Cortisone
Cortison.svg
Cortisone-3D-balls.png
Names
IUPAC name
(8S,9S,10R,13S,14S,17R)-17-Hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione
Other names
17α,21-Dihydroxypregn-4-ene-3,11,20-trione; 17α,21-Dihydroxy-11-ketoprogesterone; 17α-Hydroxy-11-dehydrocorticosterone
Identifiers
CAS Number
  • 53-06-5 YesY
3D model (Jmol)
  • Interactive image
ChEBI
  • CHEBI:16962 YesY
ChemSpider
  • 193441 YesY
ECHA InfoCard 100.000.149
IUPHAR/BPS
  • 5171
KEGG
  • D07749 YesY
MeSH Cortisone
PubChem CID
  • 222786
Properties
Chemical formula
C21H28O5
Molar mass 360.45 g·mol−1
Melting point 220 to 224 °C (428 to 435 °F; 493 to 497 K)
Pharmacology
ATC code
H02AB10 (WHO) S01BA03 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Cortisone (/ˈkɔːrtsn/ or /ˈkɔːrtzn/), also known as 17α,21-dihydroxypregn-4-ene-3,11,20-trione, is a pregnane (21-carbon) steroid hormone. It is one of the main hormones released by the adrenal gland in response to stress. In chemical structure, it is a corticosteroid closely related to cortisol. It is used to treat a variety of ailments and can be administered intravenously, orally, intraarticularly (into a joint), or transcutaneously. Cortisone suppresses the immune system, thus reducing inflammation and attendant pain and swelling at the site of the injury. Risks exist, in particular in the long-term use of cortisone.[1][2]


 







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